- Sublingual tablets provide consistent melatonin bioavailability - pharmacokinetic studies indicate that 30 to 60% of an oral dose of melatonin is metabolized via the liver9 and overall gastrointestinal absorption is variable10,11
- A singular high potency sublingual tablet is optimal for those who need higher doses of melatonin (10-20 mg)
- Derived from non-animal sources
- Refreshing, natural peppermint flavour
Serving Size: 1 sublingual tablet
|Melatonin (vegetarian source)||10 mg|
Lactose monohydrate, microcrystalline cellulose, natural peppermint flavour, croscarmellose sodium, vegetable grade magnesium stearate (lubricant).
Does Not Contain
artificial colours, preservatives, or sweeteners; no starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians.
Adults: Do not drive or use machinery for 5 hours after taking melatonin . Dissolve 1 tablet under the tongue at bedtime once per day or as directed by a health care practitioner. Consult a health care practitioner for use beyond 4 weeks.
Consult a health care practitioner prior to use if you have a hormonal disorder, diabetes, liver or kidney disease, cerebral palsy, seizure disorders, migraine, depression and/or hypertension, or if you are taking blood pressure or sedative/hypnotic medications. Do not use if you are taking immunosuppressive drugs and/or if you are pregnant or breastfeeding. Do not drive or use machinery for 5 hours after taking melatonin. If symptoms persist continuously for more than 4 weeks (chronic insomnia), consult your health care practitioner. Keep out of reach of children.
Melatonin can stimulate immune function and may reduce the efficacy of immunosuppressive drugs. Theoretically, concomitant use of melatonin with sedative/hypnotic or central nervous system depressants may be additive. However, benzodiazepines may also reduce endogenous melatonin levels. Melatonin can reduce the efficacy of blood pressure medication nifedipine GITS (Procardia XL). Case reports suggests melatonin may potentiate anticoagulant and antiplatelet medications, however, the mechanism and clinical significance are unknown. Additionally, melatonin may impair glucose utilization and increase insulin resistance in diabetic patients. However, the clinical significance of this effect on diabetics is unknown. Contraceptive drugs can increase endogenous melatonin levels. Theoretically, this may increase the effects and adverse effects of oral melatonin use. Fluvoxamine significantly inhibits the elimination of melatonin, which some researchers believe could be helpful in the treatment of refractive insomnia. However, this interaction may also cause excessive unwanted drowsiness and other adverse effects.
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