DIM® Enhanced is a microencapsulated form of diindolylmethane (DIM) designed to promote healthy estrogen balance. Curcuminoids and green tea extract are also included alongside wasabia.
Healthy hormone detoxification is a crucial part of the normal functioning of organs, including the breast. DIM is known to help stimulate natural detoxification enzymes to support healthy estrogen metabolism. As a natural component derived from indole-3-carbinole and cruciferous vegetables, DIM has been shown in clinical research to favour the production of the estrogen metabolite 2-hydroxysterone over the more deleterious 16-hydroxyestrone. DIM can also decrease the severity and duration of recurrent breast pain and promote antioxidant support. Microencapsulated DIM® by BioResponse® is a patented, absorption-enhancing formulation to ensure proper assimilation by the body. It is the only DIM with proven absorption and activity demonstrated in independently performed clinical studies.
Polyphenols in green tea, specifically the catechins, provide the primary health promoting benefits associated with green tea consumption. Catechins, most notably epigallocatechin gallate (EGCG), are effective antioxidants and decrease harmful oxidative damage. Similarly, curcuminoids are the naturally occurring bioactive compounds from turmeric. Since curcuminoids exhibit poor absorption when consumed orally, DIM® Enhanced contains a highly bioavailable curcumin complex called MERIVA®. Pharmacokinetic comparison studies have shown MERIVA® to have up to a 20-fold improvement in bioavailability versus the standard 95% turmeric extracts.
Wasabia japonica (a member of the cruciferous vegetable family) contains long chain isothiocyanates (ITCs), which are unique to wasabia.
Adults: Take 1 capsule 2 times daily with meals or as directed by your healthcare practitioner. Consult your healthcare practitioner for use beyond 12 weeks.
Each Capsule Contains:
BioResponse DIM®/MD∆ … 125 mg
3,3'-Diindolylmethane/ 3,3'-Diindolylméthane … 31.25 mg
Green Tea Leaf Extract … 200 mg
(Camellia sinensis) (20:1) (4000 mg dried equivalent)
MERIVA®/MD§ … 125 mg
Curcuminoids … 25 mg
(from Curcuma longa rhizome)
Wasabi Rhizome ... 50 mg
Non-medicinal ingredients: Hypromellose (capsule), cellulose, silica, magnesium stearate, dibasic calcium phosphate dihydrate,
starch, vitamin E, phosphatidylchloline (from sun‑ower).
BioResponse DIM® is a trademark of BioResponse, L.L.C., Boulder. CO. U.S. Patent 6,086,915.
Meriva® is a registered trademark of Indena S.p.A, Milano.
Risk Information: Do not use this product if you are pregnant or breastfeeding. Consult your healthcare practitioner prior to use if you are taking any medication or natural health products, antiplatelet medication or blood thinners, have a liver disorder, symptoms of low estrogen, an iron deficiency, gallstones, a bile duct obstruction, stomach ulcers or excess stomach acid, or are attempting to conceive. Consult your healthcare practitioner prior to use to exclude the diagnosis of a serious cause of hormonal imbalance. Consult your healthcare practitioner if symptoms persist or worsen. Rare, unpredictable cases of liver injury associated with green tea extract-containing products have been reported. Stop use and consult your healthcare practitioner if you develop symptoms of low estrogen or liver trouble such as yellowing of the skin or eyes, stomach pain, dark urine, sweating, nausea, unusual tiredness or loss of appetite. Keep out of the reach of children. Use only if safety seal is intact. Store in a cool, dry place. Contents may not package in order to accommodate required labeling. Please rely on stated quantity.