Digestive Enzymes Plus

Digestive Enzymes Plus is a blend of enzymes, present in both the stomach and the small intestine, aimed at facilitating digestion. It contains pancreatin, a mix of pancreatic enzymes including protease for the hydrolysis of proteins, amylase for the degradation of starches, and lipase for the digestion of fats. Digestive Enzymes Plus also comprises ox bile salts to aid in gut-fat absorption, and papain, a plant-derived proteolytic enzyme. Furthermore, betaine hydrochloride is found in this supplement; it is a source of hydrochloric acid, which acts in the gastrointestinal tract to activate pepsin, for the secretion of gastric acid. Digestive Enzymes Plus contains 200 mg of pancreatic enzymes (vs. 11.4 mg per capsule in Vitazan's Digestive Enzymes).

Suggested Use: 
Adults: Take 1–4 capsules daily with food or as directed by your healthcare practitioner. Take with or immediately before a meal/food. Swallow whole; do not crush or chew. Use the smallest effective dose which controls symptoms.

Each vegetable capsule contains:
Pancreatic enzymes ... 200mg
(from porcine [Sus scrofa]) (20,000 USP PC protease, 20,000 USP AGU amylase, 1,600 USP LU lipase)
Betaine hydrochloride ... 105.3 mg
Ox bile ... 64.8mg
(from Bos taurus liver), 45% cholic acids
Papain ... 3.84mg
(from papaya [Carica papaya] fruit) (384,000 FCC PU)
Pepsin A ... 32.4mg
(324,000 FCC PU)

Betaine hydrochloride equivalent to 10 drops of dilute hydrochloric acid USP*

*USP = United States Pharmacopeia

Non-medicinal ingredients: Vegetable magnesium stearate, microcrystalline cellulose and silicon dioxide in a non‑GMO vegetable capsule composed of vegetable carbohydrate gum and purified water.

Dairy free, egg free, gluten free, soy free, and yeast free. 
Cautions and warnings: Consult a health-care practitioner prior to use if you have diabetes, heart disease, or kidney problems; if you are suffering from any serious illness or disease such as pancreatitis, pancreas exocrine insufficiency or cystic fibrosis; if you have an allergy to latex or fruits (such as avocado, banana, chestnut, passion fruit, fig, melon, mango, kiwi, pineapple, peach, and tomato); if you have gastrointestinal lesions/ulcers (e.g., peptic ulcer)
or excess stomach acid; if you are taking anticoagulant agents, anti-inflammatory agents, or other enzyme products; or if you are having surgery. Consult a health-care practitioner if the symptoms persist or worsen.
Contraindications: Do not use if you are pregnant or breast-feeding; after recent surgery; if you are sensitive to pancreatic enzymes; or if you are sensitive to pork proteins.
Known adverse reactions: Hypersensitivity/allergy have been known to occur; in which case, discontinue use. Nausea, vomiting, constipation, diarrhea, abdominal pain/epigastric pain and/or heartburn have been known to occur, in which case discontinue use and consult a health-care practitioner.