5-HTP
5-Hydroxytryptophan • 100 mg

• Naturally sourced from the seed of African plant Griffonia simplicifolia
• Unlike L-tryptophan, 5-HTP readily crosses the blood-brain barrier increasing central nervous system synthesis of serotonin11
• Enteric coated to reduce the likelihood of nausea

Product Facts
Serving Size: 1 caplet

Medicinal Ingredients

L-5-Hydroxytryptophan (Griffonia simplicifolia) (seed)

100 mg

Non-Medicinal Ingredients
Dibasic calcium phosphate dihydrate, purified water, microcrystalline cellulose, enteric coating (purified water, ethylcellulose, medium chain triglycerides, oleic acid, carbohydrate gum [cellulose], glycerin, sodium alginate, stearic acid), vegetable grade magnesium stearate (lubricant).

Does Not Contain
artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten,yeast, soy, corn, egg, fish, shellfish, animal products,salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

Recommended Dose
Healthy Mood Balance: 1 caplet 3 times per day with food or as directed by a health care practitioner. To minimize the risk of gastrointestinal side effects, slowly increase up to the full dose over a period of 2 weeks. Use for a minimum of 1 week to see beneficial effects. Consult a health care practitioner for use beyond 1 year.
Sleep Aid: 1 caplet 1–2 times per day with food, 30–45 minutes prior to bedtime, or as directed by a health care practitioner.

Cautions and Warnings
Consult a health care practitioner prior to use if you are pregnant or breastfeeding or are taking carbidopa or drugs/supplements with serotonergic activity. Some people may experience diarrhea, nausea, vomiting, abdominal pain or drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. Discontinue use and consult a health care practitioner if you show signs of weakness, oral ulcers or abdominal pain accompanied by severe muscle pain, if you experience skin changes, or if symptoms persist or worsen. Consult a health care practitioner if sleeplessness persists for more than 3 weeks. Do not use if you have scleroderma. Keep out of reach of children.

Drug Interactions
Combining serotonergic drugs such as antidepressants, dextromethorphan (in cough syrups), meperidine (Demerol), tramadol and others may increase the risk of serotonergic side effects such as serotonin syndrome. Combining 5-HTP and carbidopa-levodopa (Sinement®) can increase the risk of serotonergic side effects. Carbidopa is sometimes intentionally used with 5-HTP to minimize peripheral 5-HTP metabolism and boost the amount that reaches the brain. But this combination might also increase the risk of some side effects including hypomania, restlessness, rapid speech, anxiety, insomnia, and aggressiveness. The combination of 5-HTP and carbidoba has also resulted in scleroderma-like skin reactions. Individuals using this drug combination or those who suffer from scleroderma should be monitored by a health care practitioner. Anecdotally, 5-HTP may lower blood pressure and could be additive to antihypertensive drugs.